I used to listen to the Adam Carolla podcast daily...but geez he mutated into a self indulgent right-winged flog. I mean he was always that but it just got to a point where I could no longer listen to his ignorant rants. He's repetitive and crappy guests started to hit hard too, obviously no one wanted to risk their career by going on his show. Having said the his side kick Bald Bryan was great and likeable, and was brilliant with the sound byte machine. Since I stopped listening I heard he unceremoniously dumped his news girl Allison Rosen from the show via text. Classy guy.
I always find time for Bill Burr's podcast, Gilbert Godfried's Amazing Colossal Podcast (the guy is a filthy animal, hilarious stuff), Marc Maron's WTF and Startalk Radio with Neil deGrasse Tyson.
Topics, with Michael Ian Black and Michael Showalter. Very funny. A couple of idiots discussing world issues and solving them in 30 mins or less.
The Tim Ferris show. Life hacking style of podcast.
Mohr Stories with Jay Mohr. Similar to the Marc Maron WTF podcast but less famous guests.
The Bugle. Jon Oliver and Andy are great.
A couple I used to listen two regularly was the Greg Fitzsimmons podcast and the nerdiest.
And do yourself a favour and download all the ricky gervais show seasons, radio and podcasts. Just brilliant stuff.